Grow weed, cacti, mushrooms,dmt,lsa,opies or any other tried and true natural drug. Lots of these so called drugs are worse in side effects and can be unpredictable.
Research Chemicals are basically just new drugs. Calling them RC's is a way to sell them without saying, "Hey, buy these drugs!" Some of them are alright and some might make you feel uneasy... They are new so the side effects are unknown. Cancer, limbs falling off, etc could happen. Know this - DOx chemicals (DOM, DOB, DOC, DOI) last a long time and a 24 hour peak of tripping and rolling is common. You can research the research chemicals on Erowid. I would like to try MXE which is like K but manufactured for recreational use, 2C-B which is said to be similar to E and LSD but also unlike either one, and maybe some others. Just use caution. cport420 makes a good point about unpredictability and the classic tried and true drugs are well documented so you know what you're getting yourself into with them.
Check out these two books - PIHKAL and TIHKAL. These are "Classics" from the man known as the "Father of Ecstasy".